Sangre de grado is a tree that grows in the Amazon rainforest of Peru, Ecuador, and Colombia. The sap of sangre de grado has a long history of use by indigenous people of South America. For centuries, sangre de grado were used to stop bleeding, accelerate injuries healing, and to seal and protect wounds from infection. Today sangre de grado is used in much the same way as it was centuries ago. It is recommended as an antiseptic and for healing wounds and skin disorders.